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Acupuncture for migraine prophylaxis: a randomized controlled trial.

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成果类型:
期刊论文
作者:
Li, Ying;Zheng, Hui;Witt, Claudia M.;Roll, Stephanie;Yu, Shu-guang;Yan, Jie;Sun, Guo-jie;Zhao, Ling;Huang, Wen-jing;Chang, Xiao-rong;Zhang, Hong-xing;Wang, De-jun;Lan, Lei;Zou, Ran;Liang, Fan-rong
通讯作者:
Liang, FR
作者机构:
[Huang, Wen-jing; Liang, Fan-rong; Zheng, Hui; Li, Ying; Zhao, Ling; Yu, Shu-guang] Chengdu Univ Tradit Chinese Med, Chengdu, Sichuan, Peoples R China.
[Huang, Wen-jing; Roll, Stephanie; Witt, Claudia M.] Charite Univ Med Ctr, Inst Social Med, Berlin, Germany.
[Yan, Jie; Chang, Xiao-rong; Lan, Lei] Hunan Univ Tradit Chinese Med, Changsha, Hunan, Peoples R China.
[Sun, Guo-jie; Zou, Ran; Zhang, Hong-xing] Hubei Univ Tradit Chinese Med, Wuhan, Hubei, Peoples R China.
[Witt, Claudia M.] Univ Maryland, Sch Med, Ctr Integrat Med, Baltimore, MD 21201 USA.
通讯机构:
[Liang, FR] Chengdu Univ Tradit Chinese Med, Chengdu, Sichuan, Peoples R China.
语种:
英文
期刊:
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
ISSN:
0820-3946
年:
2012
卷:
184
期:
4
页码:
401-410
文献类别:
WOS:Article
所属学科:
ESI学科类别:临床医学
入藏号:
WOS:000301465400006;PMID:22231691
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
BACKGROUND: Acupuncture is commonly used to treat migraine. We assessed the efficacy of acupuncture at migraine-specific acupuncture points compared with other acupuncture points and sham acupuncture. METHODS: We performed a multicentre, single-blind randomized controlled trial. In total, 480 patients with migraine were randomly assigned to one of four groups (Shaoyang-specific acupuncture, Shaoyang-nonspecific acupuncture, Yangming-specific acupuncture or sham acupuncture [control]). All groups received 20 treatments, which included electrical stimulation, over a period of four weeks. The primary outcome was the number of days with a migraine experienced during weeks 5-8 after randomization. Our secondary outcomes included the frequency of migraine attack, migraine intensity and migraine-specific quality of life. RESULTS: Compared with patients in the control group, patients in the acupuncture groups reported fewer days with a migraine during weeks 5-8, however the differences between treatments were not significant (p > 0.05). There was a significant reduction in the number of days with a migraine during weeks 13-16 in all acupuncture groups compared with control (Shaoyang-specific acupuncture v. control: difference -1.06 [95% confidence interval (CI) -1.77 to -0.5], p = 0.003; Shaoyang-nonspecific acupuncture v. control: difference -1.22 [95% CI -1.92 to -0.52], p < 0.001; Yangming-specific acupuncture v. control: difference -0.91 [95% CI -1.61 to -0.21], p = 0.011). We found that there was a significant, but not clinically relevant, benefit for almost all secondary outcomes in the three acupuncture groups compared with the control group. We found no relevant differences between the three acupuncture groups. INTERPRETATION: Acupuncture tested appeared to have a clinically minor effect on migraine prophylaxis compared with sham acupuncture. TRIAL REGISTRATION: Clinicaltrials.gov NCT00599586.
参考文献:
Cheung RTF, 2000, HEADACHE, V40, P473, DOI 10.1046/j.1526-4610.2000.00071.x
Wang YF, 2011, J HEADACHE PAIN, V12, P561, DOI 10.1007/s10194-011-0360-2
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