期刊论文

中文

光明中医

1003-8914

2009

24

10

1835-1837

10.3969/j.issn.1003-8914.2009.10.004

湖南省科技厅科技支撑计划项目（No:2007SK3107）；

本校为第一机构

目的：论证益肝汤保留灌肠对抗痨药所致药物性肝损害的预防作用。方法：以住院初治的肺结核患者100例为对象,随机分为实验组和对照组各50例,两组在抗结核治疗前均抽血检测肝功能,实验组在接受抗痨治疗的同时,取益肝汤保留灌肠,对照组在接受抗痨治疗的同时,用肝泰乐加维生素C口服,2周为1个疗程,连续应用2个疗程。两组在实验结束后,分别检测肝功能。结果：两组在实验结束后,肝功能指标的组间差别有高度统计学意义（P〈0.01）,药物性肝损害的发生率的组间差别有统计学意义（P〈0.05）。结论：用中药益肝汤保留灌肠,能明显改善肝功能指标,预防抗痨药所致药物性肝损害的发生。

Objective： Yigan Decoction retention enema demonstration against TB drugs due to the preventive effects of drug-induced liver injury. Methods：To hospitalized patients with newly diagnosed 100 cases of tuberculosis for the object, were randomly divided into experimental and control groups of the 50 cases, the two groups in the anti-tuberculosis treatment before pumping detect liver function, the experimental group in an anti-tuberculosis treatment at the same time, check Yigan Tang retention enema, the control group in an anti-tuberculosis tre...