期刊论文

Efficacy and safety of Ganluxiaodudan （TCM decoction） treatment in patients with chronic severe hepatitis B

中文

中西医结合肝病杂志

1005-0264

2010

20

3

135-137

10.3969/j.issn.1005-0264.2010.03.003

国家科技重大专项“十一五”课题“慢性重型肝炎证候规律及中西医结合治疗方案研究”（No.2008ZX1005-007）资助；

本校为第一机构

目的:比较清热利湿法加与不加温阳健脾药物治疗慢性重型肝炎(阳黄、湿重于热型)的疗效.方法:采用随机、对照方法,将60例中医辨证为湿重于热的慢性重型肝炎分为两组,分别给予甘露消毒丹(非温法干预组)和甘露消毒丹加附片、白术(温法干预组)治疗.结果:治疗4周,温法干预组和非温法干预组有效率分别为93.1%和72.41%.两组患者的TBil均有明显下降,温法干预组的下降幅度较非温法干预组明显,治疗前后差值分别为(228.62±89.18)和(176.70±97.94)μmol/L,两组比较,P＜0.05.PTA水平都有不同程度的升高,温法干预组PTA水平上升的幅度大于非温法干预组,上升幅度均数比较,P＜0.05.未发现温法干预组患者出现感染...

Objective：To observe the efficacy and safety of TCM decoction Ganluxiaodudan（GD） and Ganluxiaodudan plus Monkshood and Atractylodes（GDp） treatment in patients with chronic severe hepatitis B（CSHB）.Methods：Sixty patients with CSHB were randomly divided into two groups,one received GD,another GDp,for 4 weeks.Level of serum bilirubin,PTA and adverse events were observed.Results：The efficient was 93.1%（27/29）,72.41%（21/29） in group GD and GDp respectively.Level of serum bilirubin was significantly lower in both groups,but the descendin...