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BYHWD rescues axotomized neurons and promotes functional recovery after spinal cord injury in rats

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成果类型:
期刊论文
作者:
Chen, An(陈安);Wang, Hui;Zhang, Jianwei;Wu, Xiaoqiong;Liao, Jun(廖君);...
通讯作者:
Luo, Xuegang
作者机构:
[Li, Hua; Chen, An; Wang, Hui; Cai, Weijun; Wu, Xiaoqiong; Zhang, Jianwei; Luo, Xuegang] Cent S Univ, Xiangya Sch Med, Dept Anat & Neurobiol, Changsha 410013, Peoples R China.
[Liao, Jun; Chen, An] Hunan Tradit Chinese Med Univ, Dept Anat, Changsha 410007, Peoples R China.
[Ju, Gong] Fourth Mil Med Univ, Inst Neurosci, Xian 710032, Peoples R China.
通讯机构:
[Luo, Xuegang] C
Cent S Univ, Xiangya Sch Med, Dept Anat & Neurobiol, Changsha 410013, Peoples R China.
语种:
英文
关键词:
Buyang Huanwu Decoction;Axotomized neuron;Axon regeneration;Functional recovery;Spinal cord injury
期刊:
Journal of Ethnopharmacology
ISSN:
0378-8741
年:
2008
卷:
117
期:
3
页码:
451-456
机构署名:
本校为其他机构
摘要:
Ethnopharmacological relevance: Buyang Huanwu Decoction (BYHWD), a Chinese prescription that has been used for hundreds of years to treat paralysis, has gained attention recently due to its significant neuroprotective properties. Aim of the study: This study was to investigate whether BYHWD treatment protected axotomized rubrospinal neurons (RN) following spinal cord injury (SCI) in rats. Materials and methods: Adult rats received a right lateral funiculus transection at the level between C3 and C4, and were either treated with BYHWD or with distilled water (DW) via gastrogavage. Effects on RN...

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