Objective To study the applicable value of acetylglucosaminidase (NAG), adenosine deaminase (ADA), hydroxyproline (Hyp) and hyaluronate (HA) in the detection of auxiliary diagnosis of hepatic fibrosis. Methods The model of rat liver cirrhosis (LC) was induced with a combination of carbon tetrachloride (CC14), high fatty foods, and low protein foods. The four targets listed above came from 20 rats with LC and 96 patients with chronic liver diseases. The targets were then studied using colorimetric analysis with spectrophotometer and radioimmunological analysis. Results In the group of rats with...