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Randomised clinical trial: an assessment of acupuncture on specific meridian or specific acupoint vs. sham acupuncture for treating functional dyspepsia.

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WOS被引频次:48
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成果类型:
期刊论文
作者:
Ma, T T;Yu, S Y;Li, Y;Liang, F R;Tian, X P;Zheng, H;Yan, J;Sun, G J;Chang, X R;Zhao, L;Wu, X;Zeng, F
通讯作者:
Liang, F. R.
作者机构:
[Ma, T T] Chengdu Univ Tradit Chinese Med, Teaching Hosp, Chengdu, Sichuan, Peoples R China.
[Chang, X R; Yan, J] Hunan Univ Tradit Chinese Med, Changsha, Hunan, Peoples R China.
[Sun, G J] Hubei Univ Tradit Chinese Med, Wuhan, Hubei, Peoples R China.
[Liang, F R] 37 Shier Qiao Rd, Chengdu 86610075, Sichuan, Peoples R China.
通讯机构:
[Liang, F. R.] 37 Shier Qiao Rd, Chengdu 86610075, Sichuan, Peoples R China.
语种:
英文
期刊:
Alimentary pharmacology & therapeutics
ISSN:
0269-2813
年:
2012
卷:
35
期:
5
页码:
552-561
文献类别:
WOS:Article
所属学科:
ESI学科类别:药理学&毒理学;WOS学科类别:Gastroenterology & Hepatology;Pharmacology & Pharmacy
入藏号:
WOS:000299832700006;PMID:22243034
机构署名:
本校为其他机构
摘要:
BACKGROUND: Functional dyspepsia (FD) is a common disease without an established optimal treatment. AIM: To determine (i) the effect of acupuncture in relieving FD symptoms and improving life quality; (ii) the effect difference between acupoint and non-acupoint; and (iii) the effect difference among different acupoints. METHODS: A total of 712 eligible patients were included and randomly assigned to six groups (Group A: specific acupoints of the stomach meridian; Group B: non-specific acupoints of the stomach meridian; Group C: specific acupoints of alarm and transport points; Group D: specific acupoints of the gallbladder meridian; Group E: sham acupuncture of non-acupoints; and Group F: itopride). A treatment period of 4 weeks (continuous five sessions per week), and a follow-up period of 12 weeks were arranged. The outcomes were the (i) patients' response, (ii) symptoms improvement measured using the Symptom Index of Dyspepsia and (iii) quality-of-life improvement based on Nepean Dyspepsia Index. RESULTS: All groups had an improvement in dyspepsia symptoms and the QoL at the end of treatment, and the improvement was sustained for 4 weeks and 12 weeks. The overall response rate was significantly higher in acupuncture group A (70.69%), and lower in sham acupuncture group (34.75%), compared with itopride and other acupuncture groups. Similarly, the difference in symptoms and QoL improvement was significant between group A and the other acupuncture groups. CONCLUSIONS: Acupuncture is effective in the treatment of functional dyspepsia, and is superior to non-acupoint puncture. The benefit of acupuncture relies on acupoint specificity.
参考文献:
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