关键词：
perceived stress;Mobile phone addiction;Self-Control;security;college students
摘要：
ObjectiveAccording to the General Strain Theory, stress can lead to a range of problem behaviors. In the current study, we focused on the association between perceived stress and mobile phone addiction. We hypothesized that this association is mediated by low self-control and that the first path of the mediation is moderated by security. MethodsCollege students (N = 397; ages 16-21; 51.89% females) from a university in Hunan Province, China, were surveyed by cluster sampling method. The students completed the Smartphone Addiction Scale-Short Version (SAS-SV), the Depression Anxiety Stress Scale (DASS-21), the Self-Control Scale (SCS), and the Security Questionnaire (SQ) during regular class time. SPSS26.0 statistical software was used for descriptive statistics and Pearson correlation analyses, the SPSS macro PROCESS was used to test the mediating effects of self-control and the moderating role of security. ResultsMediation analysis showed that as expected, perceived stress was associated with lower self-control, which in turn was associated with a higher risk for mobile phone addiction. Also as expected, moderated mediation analysis indicated that the association between perceived stress and self-control was moderated by security. Specifically, the relationship between perceived stress and self-control was stronger for low security. ConclusionThis study provides useful insight into the understanding of how perceived stress increases the risk of mobile phone addiction. The results are consistent with the General Strain Theory and further indicate that concrete approaches are required for the prevention and intervention to reduce mobile phone addiction among college students.
期刊：
Current Psychology,2022年41(1):298-306 ISSN：1046-1310
通讯作者：
He, Jinbo
作者机构：
[Chen, Gui] Hengyang Normal Univ, Coll Educ Sci, Hengyang 421002, Peoples R China.;[Fan, Xitao; He, Jinbo] Chinese Univ Hong Kong Shenzhen, Sch Humanities & Social Sci, Shenzhen 518172, Peoples R China.;[Zhang, Bin] Hunan Univ Chinese Med, Dept Appl Psychol, Changsha 410208, Peoples R China.
通讯机构：
[He, Jinbo] C;Chinese Univ Hong Kong Shenzhen, Sch Humanities & Social Sci, Shenzhen 518172, Peoples R China.
关键词：
Body weight, body mass index (BMI);Body dissatisfaction;Weight-related teasing;Adolescents
作者机构：
[Gong, Jingbo] Shanghai Changning Mental Hlth Ctr, Shanghai 200335, Peoples R China.;[Gong, Jingbo; Zhao, Lishun; Luo, Yanhong] Hunan Univ Chinese Med, Dept Appl Psychol, Changsha, Hunan, Peoples R China.;[He, Yuqiong] Second Xiangya Hosp Cent South Univ, Natl Clin Res Ctr Mental Disorders, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.;[He, Yuqiong] Cent South Univ, Dept Psychiat, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.;[Zhou, Lihua] Hengyang Normal Univ, Coll Educ Sci, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Liu, Jianbo] D;Department of Child Psychiatry of Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen Institute of Mental Health, Shenzhen Key Laboratory of Mental Health, Shenzhen, China. Electronic address:
摘要：
Although psychotic-like experiences (PLEs) are transient and not pathognomonic for psychiatric disorders, they may increase the risk of concurrent and future psychiatric disorders. However, the prevalence of PLEs and the different effects of PLE subtypes on mood outcomes are still unclear. Thus, this study seeks to investigate the prevalence of PLE subtypes and explore their relationship with the use of specific emotion regulation strategies and the level of affective lability among college students. The history of PLEs, the level of affective lability, and the use of specific emotion regulation strategies were assessed via self-reported questionnaires, and 1905 college students and 1812 college students were included in separate analyses. This study found that 14.44% of college students reported ever experiencing any of the five PLEs, with males reporting more PLE symptoms and a higher number of PLEs than females. Different PLE subtypes had different effects on the use of specific emotion regulation strategies (cognitive reappraisal or suppression) and the level of affective lability and also showed gender differences. Cognitive reappraisal and suppression differently predicted affective lability in males and females, and cognitive reappraisal mediated the relationship between hearing voices in PLEs and affective lability in males. In conclusion, PLEs were common in Chinese college students and gender differences were revealed in the prevalence of PLE subtypes. PLEs were associated with the use of specific emotion regulation strategies and the level of affective lability. Cognitive reappraisal may be a promising target for intervention aimed at relieving the effect of PLEs in non-clinical individuals.
通讯机构：
Neuropsychiatric Imaging Center, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen, China
关键词：
Introduction;Materials and Methods;Results;Discussion;Conclusion;Abstract;Data Availability;Additional Points;Ethical Approval;Consent;Disclosure;Conflicts of Interests;Authors’ Contributions;Funding Statement;Acknowledgements;Acknowledgments;Supplementary Materials;Reference;Dataset Description;Dataset Files;Abstract;Introduction;Introduction and Materials;Introduction and Methods;Materials;Materials and Methods;Methods;Results;Discussion;Results and Discussion;Discussion and Conclusion;Results and Conclusion;Conclusion;Conclusions;Data Availability;Additional Points;Ethical Approval;Consent;Disclosure;Conflicts of Interest;Authors’ Contributions;Funding Statement;Acknowledgements;Supplementary Materials;References;Appendix;Abbreviations;Preliminaries;Introduction and Preliminaries;Notation;Proof of Theorem;Proofs;Analysis of Results;Examples;Numerical Example;Applications;Numerical Simulation;Model;Model Formulation;Systematic Palaeontology;Nomenclatural Acts;Taxonomic Implications;Experimental;Synthesis;Overview;Characterization;Background;Experimental;Theories;Calculations;Model Verification;Model Implementation;Geographic location;Study Area;Geological setting;Data Collection;Field Testing;Data and Sampling;Dataset;Literature Review;Related Works;Related Work;System Model;Methods and Data;Experimental Results;Results and Analysis;Evaluation;Implementation;Case Presentation;Case Report;Search Terms;Case Description;Case Series;Background;Limitations;Additional Points;Case;Case 1;Case 2 etc.;Concern Details;Retraction Details;Copyright;Related Articles
摘要：
Objective. This study is aimed at exploring the regional changes in brain cortical morphology (thickness, volume, and surface area) in the early-blind adolescents (EBAs) by using the surface-based morphometric (SBM) method. Methods. High-resolution structural T1-weighted images (T1WI) of 23 early-blind adolescents (EBAs) and 21 age- and gender-matched normal-sighted controls (NSCs) were acquired. Structural indices, including cortical thickness (CT), cortical volume (CV), and surface area (SA), were analyzed by using FreeSurfer software, and the correlations between structural indices and the blindness duration were computed by Pearson correlation analysis. Results. Compared to controls, EBAs had significantly reduced CV and SA mainly in the primary visual cortex (V1) and decreased CV in the left vision-related cortices (r-MFC). There were no regions that EBAs had a significantly larger CV or SA than NSCs. EBAs had significantly increased CT in the V1 and strongly involved the visual cortex (right lateral occipital gyrus, LOG.R) and the left superior temporal gyrus (STG.L), while it had decreased CT in the left superior parietal lobule (SPL.L) and the right lingual gyrus (LING.R). Additionally, no correlation was found between cortical morphometric measures and clinical variables in the EBA group. Conclusions. SBM is a useful method for detecting human brain structural abnormalities in blindness. The results showed that these structural abnormalities in the visual cortex and visual-related areas outside the occipital cortex in the EBAs not only may be influenced by neurodevelopment, degeneration, plasticity, and so on but also involved the interaction of these factors after the early visual deprivation.
期刊：
Journal of Advanced Nursing,2022年78(12):4071-4081 ISSN：0309-2402
通讯作者：
Jie Zhang<&wdkj&>Jingping Zhang
作者机构：
[Zhang, Jingping; Li, Juan; Yin, Yizhen] Cent South Univ, Xiangya Nursing Sch, Changsha 410013, Hunan, Peoples R China.;[Lyu, Mengmeng] Natl Univ Singapore, Alice Lee Ctr Nursing Studies, Yong Loo Lin Sch Med, Singapore, Singapore.;[Zuo, Man] Guangdong Prov Peoples Hosp, Dept Resp Med, Heyuan Branch, Heyuan, Peoples R China.;[Yao, Shuyu] Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou, Peoples R China.;[Li, Hui] Sichuan Univ, West China Hosp, Dept Orthoped, West China Sch Nursing, Chengdu, Peoples R China.
通讯机构：
[Jie Zhang] S;[Jingping Zhang] X;Xiangya Nursing School, Central South University, Changsha, P.R. China<&wdkj&>School of Nursing, Hunan University of Chinese Medicine, Changsha, P.R. China
关键词：
COVID-19;latent class analysis;nurses;work engagement
摘要：
AIM: The aim was to examine the subgroups of work engagement in frontline nurses during the COVID-19 pandemic. BACKGROUND: The pandemic may affect the work engagement of nurses who have direct contact with infected patients and lead to a poor quality of care. Identifying classification features of work engagement and tailoring interventions to support frontline nurses is imperative. DESIGN: This study utilized a cross-sectional study design. METHODS: Three hundred fifty-five nurses were enrolled in this cross-sectional study from 14 February to 15 April 2020. A latent profile analysis was performed to identify classification features of work engagement. Multiple logistic regression analyses were used to examine predictors of profile membership. RESULTS: A four-profile model provided the best fit. The four profiles were titled 'low work engagement' (n=99), 'high vigour-low dedication and absorption' (n=58), 'moderate work engagement' (n=63) and 'high work engagement' (n=135). A regression analysis suggested that young nurses and nurses who were the only children of their family were more likely to be in the 'low work engagement' and 'high vigour-low dedication and absorption' groups. CONCLUSION: This study highlights the importance of tailoring interventions for frontline supporting nurses by considering their distinct work engagement patterns, especially during the COVID-19 pandemic, to improve the promotion of work satisfaction and quality of care. IMPACT: This was the first study to explore the latent profiles of work engagement in frontline nurses during the COVID-19 pandemic. Over 40% of nurses were in the 'low work engagement' and 'high vigour-low dedication and absorption' groups and reported low levels of work engagement. Understanding different patterns of work engagement in frontline nurses can help nursing managers provide emotional, material and organizational support based on the features of each latent profile, which may improve the quality of care and patient safety.
期刊：
Journal of Affective Disorders,2022年319:244-251 ISSN：0165-0327
通讯作者：
Xiongzhao Zhu
作者机构：
[Yu, Quanhao; Fan, Jie; Wang, Xiang; Liu, Qian; Lu, Jingjie; Zhu, Xiongzhao; Liu, Xingze; Gao, Feng; Han, Yan] Cent South Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Hunan, Peoples R China.;[Yu, Quanhao; Fan, Jie; Wang, Xiang; Liu, Qian; Lu, Jingjie; Zhu, Xiongzhao; Liu, Xingze; Gao, Feng; Han, Yan] Cent South Univ, Med Psychol Inst, Changsha, Hunan, Peoples R China.;[Yu, Quanhao; Fan, Jie; Wang, Xiang; Liu, Qian; Lu, Jingjie; Zhu, Xiongzhao; Liu, Xingze; Gao, Feng; Han, Yan] Natl Clin Res Ctr Mental Disorders, Changsha, Hunan, Peoples R China.;[Yao, Rui] Hunan Univ Chinese Med, Ctr Psychol Dev & Serv, Changsha, Hunan, Peoples R China.;[Zhu, Xiongzhao] Cent South Univ, Xiangya Hosp 2, Med Psychol Ctr, Renmin Middle Rd 139, Changsha 410011, Hunan, Peoples R China.
通讯机构：
[Xiongzhao Zhu] M;Medical Psychological Center, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China<&wdkj&>Medical Psychological Institute of Central South University, Changsha, Hunan, China<&wdkj&>National Clinical Research Center for Mental Disorders, Changsha, Hunan, China
关键词：
Threat;Deprivation;Depressed mood;Anhedonia;Latent growth curve model
摘要：
Background/aim: There is growing awareness that specific childhood trauma (CT) may confer to the unique risk of depression, but little is known about this. The present study seeks to provide insight into how CT subtypes may impact distinct depressive symptoms over time based on the dimensional model of adversity (DMA).Methods: A total of 3535 college freshmen participated in a 2-year, four waves longitudinal tracking study. A conditional parallel latent growth curve model (LGCM) was constructed to examine the impacts of different types of CT (threat and deprivation) on the development of depressed mood and anhedonia, and whether these relationships vary across gender.Results: Our findings revealed that threat and deprivation could differentially relate to depressed mood and anhedonia. Both threat and deprivation predicted initial depressed mood levels (beta = 0.309, p < 0.001; beta = 0.175, p < 0.001, respectively) and its trajectory (beta = -0.139, p = 0.068; beta = -0.168, p < 0.05, respectively). Only deprivation predicted anhedonia levels (beta = 0.318, p < 0.001) and trajectory (beta = -0.218, p < 0.001). This pattern of relationships between CT and depressive symptoms varied across gender.Conclusion: These findings highlight specific pathways and symptomatic manifestations of the impacts of different CT subtypes on depression and are consistent with the hypothesis of DMA. Threat and deprivation predicted more severe depressed mood, whereas deprivation uniquely conferred to the risk of depression via elevated anhedonia. Meanwhile, the deleterious effects of CT would persist during early adulthood. Gender differences were also discussed.
作者机构：
[Li, Xing; Li, Ao; Yu, Xu-Dong; Zhou, Yu; He, Zhiming; Wang, Le; Shu, Xinhua] Shaoyang Univ, Sch Basic Med Sci, Shaoyang 422000, Peoples R China.;[Tan, Zhoujin; Li, Xiao-Ya] Hunan Univ Chinese Med, Coll Chinese Med, Changsha 410208, Hunan, Peoples R China.;[Shu, Xinhua; Reilly, James] Glasgow Caledonian Univ, Dept Biol & Biomed Sci, Glasgow City G4 0BA, Scotland.;[Xiao, Zhi-Yong] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Crit Care Med, Hengyang 421001, Hunan, Peoples R China.
通讯机构：
[Zhi-Yong Xiao] T;[Xinhua Shu] S;The First Affiliated Hospital,Department of Critical Care Medicine,Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China<&wdkj&>School of Basic Medical Sciences, Shaoyang University, 422000, Shaoyang, China<&wdkj&>Department of Biological and Biomedical Sciences, Glasgow Caledonian University, G4 0BA, Glasgow, United Kingdom
摘要：
Trans-urocanic acid (trans-UCA) is an isomer of cis-UCA and is widely distributed in the brain, predominantly in the hippocampus and prefrontal cortex. Previous studies have investigated the role of trans-UCA in non-spatial memory; however, its influence on spatial memory remains unclear. In the present study, network pharmacology strategy and behavioral testing were used to evaluate the role of trans-UCA in spatial memory and predict its possible mechanism. The results showed that there are 40 intersecting targets between trans-UCA and spatial memory identified by several databases and Venn diagram, indicating that trans-UCA may be involved in spatial memory. Behavioral results show that trans-UCA facilitates spatial working memory in the Y-maze test as well as spatial recognition memory acquisition, consolidation and retrieval in an object location recognition (OLR) task. Furthermore, PPI (protein-protein interaction) network analysis, GO (gene ontology) and KEGG (Kyoto encyclopedia of genes and genomes) pathway enrichment analyses show that the molecular mechanisms underlying the enhancing effect of trans-UCA on spatial memory are mainly associated with the regulation of insulin, mitogen-activated protein kinase (MAPK) and nuclear factor Kappa B (NF-κB) signaling pathways, serotonergic synapse and arginine and proline metabolism. The results of this study suggest that trans-UCA facilitates spatial memory in the Y-maze test and OLR task and may offer therapeutic potential for Alzheimer's disease (AD). The underlying mechanisms predicted by network pharmacology should be further verified.
期刊：
Frontiers in Psychiatry,2022年13:1037588 ISSN：1664-0640
作者机构：
[Liao, Xiaolin; He, Ying; Wang, Yuhong; Zou, Manshu] Hunan Univ Chinese Med, Inst Innovat & Appl Res Chinese Med, Changsha, Peoples R China.;[Han, Yuanshan] Hunan Univ Chinese Med, Dept Sci Res, Hosp 1, Changsha, Peoples R China.;[Wang, Yuhong] Hunan Prov Key Lab Prevent & Treatment Depress Dis, Changsha, Peoples R China.;[Wang, Yuhong] Hunan Key Lab Power & Innovat Drugs, State Key Lab Minist Training Bases, Changsha, Peoples R China.
关键词：
COX-2;Depression;Pro-inflammatory cytokines;mechanism of action;cox-2 inhibitors
摘要：
Depressive Disorder is a common mood disorder or affective disorder that is dominated by depressed mood. It is characterized by a high incidence and recurrence. The onset of depression is related to genetic, biological and psychosocial factors. However, the pathogenesis is still unclear. In recent years, there has been an increasing amount of research on the inflammatory hypothesis of depression, in which cyclo-oxygen-ase 2 (COX-2), a pro-inflammatory cytokine, is closely associated with depression. A variety of chemical drugs and natural products have been found to exert therapeutic effects by modulating COX-2 levels. This paper summarizes the relationship between COX-2 and depression in terms of neuroinflammation, intestinal flora, neurotransmitters, HPA axis, mitochondrial dysfunction and hippocampal neuronal damage, which can provide a reference for further preventive control, clinical treatment and scientific research on depression.
