摘要：
The invention discloses a medicine-separated moxibustion device. The device comprises a bowl rim, a bowl body, a bowl bottom, a bowl cover and an acupuncture point detection device, wherein the bowl bottom and the bowl body are integrated, the bowl cover is matched with the bowl rim, the bowl cover is provided with a hole, and the hole is internally provided with a threaded sleeve; the inner surface of the bowl bottom is provided with a motor, an output shaft of the motor is fixedly connected with a worm gear, the surface of the worm gear is rotationally connected with a threaded rod, one end of the threaded rod stretches out of the hole in the bowl cover, and the other end of the threaded rod is provided with a moxa cone frame; the inner surface of the bowl body is uniformly coated with an aluminum coating, and the surface of the aluminum coating is coated with aluminum polyester thin film; the bowl bottom is provided with a center hole, the acupuncture point detection device is arranged in the center hole, the bowl body is provided with an opening, a groove is formed between the center hole and the opening, and the acupuncture point detection device slides into and out of the groove. The medicine-separated moxibustion device has the advantages that the design is reasonable, the use is safe, the therapeutic effect of medicine-separated moxibustion can be effectively improved, the operation during the medicine-separated moxibustion is simple and convenient, and the skin can be prevented from being scalded by moxa ashes.
期刊：
COCHRANE DATABASE OF SYSTEMATIC REVIEWS,2017年2017(8) ISSN：1469-493X
通讯作者：
Liang, F.-R.
作者机构：
[Liu, M.] Hunan University of Chinese Medicine, Acupuncture and Tuina College, Xiaozui Rd, Hanpu District, Changsha, Hunan, 41007, China;[Li, L.; Wang, C.C.] The Chinese University of Hong Kong, Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Shatin, New Terrorities, Hong Kong;[Leung, P.C.] The Chinese University of Hong Kong, Institute of Chinese Medicine, State Key Laboratory of Phytochemistry and Plant Resources in West China, Shatin, Hong Kong;[Liu, M.; Lan, L.; Liang, F.-R.] Chengdu University of Traditional Chinese Medicine, Acupuncture and Tuina College, 37#, Shi'er Qiao Road, Chengdu, Sichuan Province, 610075, China;[Ren, Y.-L.] Chengdu University of Traditional Chinese Medicine, Information Retrieval and Library, 37 Shi-er-qiao Road, Jinniu District, Chengdu, Sichuan Province, 610075, China
通讯机构：
Chengdu University of Traditional Chinese Medicine, Acupuncture and Tuina College, 37#, Shi'er Qiao Road, Chengdu, Sichuan Province, China
作者机构：
[Huan Zhong; Mai-lan Liu; Mi Liu; Xiao-rong Chang] School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, China;[Jian Xiong; Shan-shan Zuo; Zhi-ying Gao] Acupuncture-moxibustion Department, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Changsha, China;[Chang She] School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, China<&wdkj&>Acupuncture-moxibustion Department, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Changsha, China
通讯机构：
[Xiao-rong Chang] S;School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, China
摘要：
Objective: To observe the clinical effect of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of dorsal wrist ganglion (DWG). Methods: A total of 63 patients with DWG were randomized into a treatment group (n=32) and a control group (n=31). Cases in the control group were treated with fire needle therapy. Based on the therapy given to the control group, cases in the treatment group were additionally given wheat grain-sized cone moxibustion therapy. Then the therapeutic efficacies and recurrence rate were evaluated. Results: After treatment, the overall effective rate was 93.8% in the treatment group, versus 77.4% in the control group, and the between-group comparison showed a statistical significance (P<0.05); 6 months after the treatment, the recurrence rate in the treatment group was obviously lower than that in the control group (P<0.05). Conclusion: The long-term and short-term effects of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of DWG are better than those of fire needle therapy alone, and therefore, worth popularizing.
通讯机构：
[Dong, JY; Yang, ZB] X;Xiamen Univ, Dept Elect Sci, Xiamen 361005, Peoples R China.;Xiamen Univ, Dept Tradit Chinese Med, Xiamen 361005, Peoples R China.
摘要：
Chronic atrophic gastritis (CAG) is a common gastrointestinal disease which has been considered as precancerous lesions of gastric carcinoma. Previously, electro-acupuncture stimulation has been shown to be effective in ameliorating symptoms of CAG. However the underlying mechanism of this beneficial treatment is yet to be established. In the present study, an integrated histopathological examination along with molecular biological assay, as well as 1H NMR analysis of multiple biological samples (urine, serum, stomach, cortex and medulla) were employed to systematically assess the pathology of CAG and therapeutic effect of electro-acupuncture stimulation at Sibai (ST 2), Liangmen (ST 21), and Zusanli (ST 36) acupoints located in the stomach meridian using a rat model of CAG. The current results showed that CAG caused comprehensive metabolic alterations including the TCA cycle, glycolysis, membrane metabolism and catabolism, gut microbiota-related metabolism. On the other hand, electro-acupuncture treatment was found able to normalize a number of CAG-induced metabolomics changes by alleviating membrane catabolism, restoring function of neurotransmitter in brain and partially reverse the CAG-induced perturbation in gut microbiota metabolism. These findings provided new insights into the biochemistry of CAG and mechanism of the therapeutic effect of electro-acupuncture stimulations.
作者机构：
[佘畅; Guo, Anlin; 刘密; 刘迈兰; 章薇; 钟欢; 汪厚莲] College of Acupuncture-Moxibustion and Tuina, Hunan University of CM, Changsha 410007, China;[常小荣] College of Acupuncture-Moxibustion and Tuina, Hunan University of CM, Changsha 410007, China. xrchang1956@163.com
作者机构：
School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, 410208;Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, 200030;[贲定严; 梁昊; 刘密; 刘琼; 刘迈兰; 常小荣] School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, 410208;[孙天爱; 刘慧荣; 吴焕淦] Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, 200030
通讯机构：
School of Acupuncture, Moxibustion & Tuina, Hunan University of Chinese Medicine, Changsha, China
摘要：
Objective: To explore the beneficial regulatory effect of mild moxibustion from different distances at Zusanli (ST 36) of healthy population on the functions of temperature-related brain regions. Methods: In 20 recruited healthy subjects, the change of the temperature-related brain regions induced by mild moxibustion from different distances at Zusanli (ST 36) was observed by functional magnetic resonance imaging (fMRI). Results: In comparison of the values in amplitude of low-frequency fluctuation (fALFF) during and before moxibustion, it has been found that in moxibustion of 2 cm distance, fALFF value increased in the brain regions of the left anterior cingulated cortex and lateral surrounding cerebral regions, and fALFF value decreased in the cerebral regions of the peripheral cortex of the calcarine fissure; in moxibustion of 3 cm distance, fALFF value increased in the brain regions of the right and medial side and paracingulated gyrus, and fALFF value decreased in the cerebral zone of the left middle temporal gyrus; in moxibustion of 4 cm distance, fALFF value increased in the brain regions of the right and medial and paracingulated gyrus; and in moxibustion of 5 cm distance, fALFF value increased in the brain regions of the left hippocampus. In comparison of the value of regional homogeneity (ReHo), it has been found that in moxibustion of 2 cm distance, ReHo value increased in the cerebral zone of the posterior lobe of the right cerebellum, and ReHo value decreased in the cerebral zone of the right occipital lobe; in moxibustion of 3 cm distance, ReHo value increased in the brain regions of the left cerebellar posterior lobe and left frontal lobe, and ReHo value decreased in the cerebral zone of the right inferior temporal gyrus; in moxibustion of 4 cm distance, ReHo value increased in the brain regions of the right superior frontal gyrus and ReHo value decreased in the brain regions of the right parietal lobe and angular gyrus; in moxibustion of 5 cm distance, ReHo value increased in the cerebral zone of the right frontal lobe and ReHo value decreased in the cerebral zone of the right brainstem. Conclusion: In moxibustion of 3 cm distance, the changes in the brain regions basically conform to the transmission route of body trunk temperature.
作者机构：
[Zeng, Fang; Lan, Lei; Liang, Fanrong; Li, Zhengjie; Guo, Taipin; Wu, Feng; Li, Ying; Yin, Tao; Gao, Yujie; Yang, Jie; Dong, Mingkai] Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China.;[Jorgenson, Kristen; Kong, Jian; Makris, Nikos] Harvard Med Sch, Dept Psychiat, Massachusetts Gen Hosp, Boston, MA 02115 USA.;[Jorgenson, Kristen; Kong, Jian; Makris, Nikos] Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA.;[Liu, Mailan] Hunan Univ Chinese Med, Acupuncture & Tuina Sch, Changsha, Hunan, Peoples R China.;[Gong, Qiyong] Sichuan Univ, West China Hosp, Huaxi MR Res Ctr, Chengdu, Sichuan, Peoples R China.
通讯机构：
[Liang, Fanrong] C;[Kong, Jian] H;[Kong, Jian] M;Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China.;Harvard Med Sch, Dept Psychiat, Massachusetts Gen Hosp, Boston, MA 02115 USA.
关键词：
Migraine;Amplitude of low-frequency fluctuations;Brainsterm;Trigeminocervical complex;Acupuncture;Resting state fMRI
摘要：
Migraine is a common neurological disease with a high prevalence and unsatisfactory treatment options. The specific pathophysiological mechanisms of migraine remain unclear, which restricts the development of effective treatments for this prevalent disorder. The aims of this study were to 1) compare the spontaneous brain activity differences between Migraine without Aura (MwoA) patients and healthy controls (HCs), using amplitude of low-frequency fluctuations (ALFF) calculation method, and 2) explore how an effective treatment (verum acupuncture) could modulate the ALFF of MwoA patients. One hundred MwoA patients and forty-six matched HCs were recruited. Patients were randomized to four weeks' verum acupuncture, sham acupuncture, and waiting list groups. Patients had resting state BOLD-fMRI scan before and after treatment, while HCs only had resting state BOLD-fMRI scan at baseline. Headache intensity, headache frequency, self-rating anxiety and self-rating depression were used for clinical efficacy evaluation. Compared with HCs, MwoA patients showed increased ALFF in posterior insula and putamen/caudate, and reduced ALFF in rostral ventromedial medulla (RVM)/trigeminocervical complex (TCC). After longitudinal verum acupuncture treatment, the decreased ALFF of the RVM/TCC was normalized in migraine patients. Verum acupuncture and sham acupuncture have different modulation effects on ALFF of RVM/TCC in migraine patients. Our results suggest that impairment of the homeostasis of the trigeminovascular nociceptive pathway is involved in the neural pathophysiology of migraines. Effective treatments, such as verum acupuncture, could help to restore this imbalance.
