Objective: To investigate the Ningshen-Wendan decoction to the expression of neuronal apoptosis gene bax, bcl-2, of the schizophrenia model rat hippocampal. Methods: 40 SD rats were randomly divided into four groups: normal group, model group. Ning Shen-wendan group, chlopromazine group. Each group were administered 1 times / d, 21d, after the last day of dosing lh intraperitoneal injection of saline, normal group 2mg·kg^-1, ip the other three groups intraperitoneal injection of apomorphine hydrochloride half water 2mg·kg^-1, observed afte...