Objectires:Observe the changes in serum estradiol and osteoprotegerin(OPG) of the female rats with both ovaries removed (ovariectomy). Method: making Ovariectomized model with ovariectomy,and killed them after 13 weeks ' feeding. Result :Zhuang Gu Zhi Tong Prescripition group increasing both the estradiol and osteoprotegerin(OPG) levels,with significant difference compared with model group ( P 〈 0. 05 ). Conclusion : Zhuang Gu Zhi Tong Prescripition plays the role of anti-osteoporosis by increasing the conten...