期刊论文

中文

中国中医基础医学杂志

1006-3250

2014

20

10

1344-1347

本校为其他机构

目的:观察和评价柴胡龙牡汤对Lewis肺癌小鼠的治疗作用。方法:将40只C57BL/6J小鼠常规接种Lewis肺癌,造模成功后按随机数字表法分为柴胡龙牡汤组、模型组、顺铂对照组和恩度联合NP对照组4组。治疗时间均为2周。称瘤重计算抑瘤率,统计肺部结节数量并计算抗肺转移率,用MTT法检测肿瘤细胞的增殖能力、血液中红细胞、血小板、白细胞的比值和对脾脏中自然杀伤细胞活性、IFN-γ和IL-10含量及T淋巴细胞比值的影响。结果:柴胡龙牡汤组肿瘤质量和肺部转移结节数量明显减少(P < 0. 05);柴胡龙牡汤组在第2~3天的肿瘤细胞数目明显低于模型组(P < 0. 05);模型组、顺铂对照组和恩度联合NP治疗组自然杀伤细胞活...

Objective： To observe and evaluate Chai Hu Long Mu Decoction radiation therapy and cisplatin efficacy of Lewis lung carcinoma in mice. Methods： The 40 C57 BL /6J mice inoculated with Lewis lung routine,successful modeling were randomly divided into four groups,namely Chai Hu Long Mu Decoction group,model group,cisplatin control group and the control group endostatin combined with NP. Treatment time is 2 weeks. The tumor weight inhibition rate was calculated,the number of pulmonary nodules statistical computing anti lung metastasis,tumor cells...