期刊论文

Effect of cake separated moxibustion on T cell subsets in peripheral blood of rats with chronic bronchitis

中文

中国中医基础医学杂志

1006-3250

2020

26

01

37-40

10.3969/j.issn.1006-3250.2020.01.015

湖南省教育厅科学研究优秀青年项目（18B257）-从促炎因子→NF-kB→UPS途径探讨艾灸对胃癌恶病质大鼠骨骼肌消耗的治疗作用;湖南省教育厅创新课题项目（CX2017B452）-新型黄芪多糖药饼灸贴对慢支炎模型大鼠TNF-α、IL-1等因子的影响；

本校为第一机构

目的:观察隔药饼灸对慢性支气管炎模型大鼠外周血中T细胞亚群含量的影响,探讨隔药饼灸防治慢性支气管炎的可能机制。方法:48只SD大鼠随机分为空白组、模型组、隔药饼灸组、核酪口服液组4组各12只,采用改良烟熏法复制慢性支气管炎大鼠模型,流式细胞术检测血清中T细胞亚群含量变化。结果:与空白组比较,模型组大鼠外周血中CD_4~+、CD_8~+、CD_4~+/CD_8~+ 明显降低;与模型组比较,隔药饼灸组、核酪口服液组CD_4~+、CD_8~+ 及CD_4~+/CD_8~+ 升高;与核酪口服液组比较,隔药饼灸组CD_4~+、CD_8~+、CD_4~+/CD_8~+ 升高更明显。结论:隔药饼灸可能通过上调外周血中CD_4~+、CD_8~+ T细胞亚群含量,提高CD_4~+/...

Objective:To observe the effect of herbal-cake separated moxibustion on the content of T-cell subsets in the blood of rats with chronic bronchitis,and explore the possible mechanism of prevention and treatment of chronic bronchitis by herbal-cake separated moxibustion.Methods 48 SD rats were randomly divided into blank group,model group,herbalcake separated group and nuclear casein liquid group,12 rats in each group.The chronic bronchitis model was established by improved fumigation.Flowcytometry was used to detect the change of T cell subgroup in serum.Results Compared with the blank group,CD...