A 78-year-old male presented malignant melanoma on the right foot for 1 year,and a painful mass on the right heel for 2 days.Dermatological conditions:a nodular mass on the right heel was observed with ulcer and exudation surface.Skin biopsy showed malignant melanoma(nodular type)with ulceration.The diagnosis of acral melanoma stage Ⅳ was made.After 9 cycles of immunotherapy with toripalimab,the mass subsided,large piece of vitiligo-like leukoderma with sharp margin were revealed on the origin and surrounding region.Because of the cardiac musc...
