期刊论文

中文

中国当代医药

1674-4721

2009

16

16

25-27

10.3969/j.issn.1674-4721.2009.16.013

湖南省科技计划资助项目（编号2007JT3021）；

本校为第一机构

目的:观察益心泰丸对慢性心力衰竭大鼠血浆中PRA、AngⅡ、ALD含量影响.方法:采用腹主动脉缩窄法建立慢性心力衰竭的动物模型.将造模成功的大鼠随机分为五组:模空组、益心泰丸高剂量组、益心泰丸中剂量组、益心泰丸低剂量组和科素亚对照组,每组10只;另设一组正常对照组10只.对各组动物分别用药4周后(除正常对照组)测定血浆中PRA、AngⅡ、ALD含量.结果:益心泰丸和科素亚组与模型组比较,血浆中PRA、AngⅡ、ALD含量均低于模型组(P

Objective： This experiment aimed at observing,through animal experiments Yixintai Traditional Chinese Medicine Pill on cardiac function in rats with chronic heart failure,plasma PRA, Ang Ⅱ, ALD. Methods： The use of abdominal aorta act set up chronic congestive heart failure animal model. The success of the model rats were randomly divided into five groups, group modulus space, high-dose group of Chinese medicine, Chinese medicine in the dose group, Chinese medicine, low-dose group and western medicine, 10 in each group; separated a group of ...