Objective To analyze the effect of probiotics on the treatment of functional constipation. Methods Litera-ture data meeting the inclusion criteria were given the Meta-analysis using the software of Review manager 5.2,22 arti-cles which were published in recent years and conformed with the relevant criteria were reviewed;there were 2070 pa-tients and they were divided into the experiment group (n=1047,the probiotics treatment) and control group (n=1023,the basic treatment).The difference in the curative effect between the two groups was analyzed to learn the efficacy of pro-biotics on functiona...