期刊论文

中文

世界中医药

1673-7202

2013

8

7

731-733

10.3969/j.issn.1673-7202.2013.07.005

973;2009CB523002:国家重点基础研究发展计划（973计划）

本校为第一机构

目的:观察四磨汤有效成分(槟榔碱、乌药醚内酯、橙皮苷及木香烃内酯)对慢性应激小鼠胃肠运动功能的影响.方法:将144只小鼠随机分为正常组(8只)和造模组(136只),模型小鼠给予不可预知的慢性应激造模21d后随机分为模型组、四磨汤组及四磨汤成分组(15组)共17组;造模第15天起给药7d后,检测各组小鼠的胃肠运动功能.结果:模型组胃内残留率升高,小肠推进率降低,与正常组及四磨汤组比较差异均有统计学意义(P

Objective： To observe effect of effective substances of Simotang （arecoline,linderane,hesperidin and costunolide） on gas-trointestinal motility function in mice under chronic stress. Methods： 144 mice were divided into normal group （n=8） and model group （n=136） . Model group was under unpredictable chronic stress,after 21d,divided to model group,Simo decoction group and 15 substances groups. 7days after medication,gastrointestinal motility were assessed. Results： The model group showed slower gastric empty- ing and slower intestinal pr...