期刊论文

中文

世界中医药

1673-7202

2019

14

3

515-520

10.3969/j.issn.1673-7202.2019.03.001

81574077:国家自然科学基金 :湖南省大学生研究性学习 2017-1034:创新性实验项目

本校为第一机构

目的:观察艾灸对胃荷瘤大鼠外周血中CD4~+、CD4~+CD25~+T淋巴细胞亚群的影响。方法:将50只健康SPF级SD大鼠,雌雄各半,随机分为空白组、假手术组、模型组、艾灸组和红外组5组,每组10只。利用Walker-256细胞来源的实体瘤组织移植胃部制备模型。模型成功后,艾灸组予以悬灸中脘、胃俞等穴位;红外组予以短波红外线照射腹部胃脘及背部胃脘投影区;其余组捆绑束缚。干预20 min/次,1次/d,持续21 d。干预结束后,眼眶采血,流式细胞技术测定外周血中CD4~+、CD4~+CD25~+T淋巴比例。处死动物,测算胸腺指数及肿瘤体积生长抑制率。结果:与空白组比较,模型组动物生存状态变差,胸腺指数增加,外周血中CD4~+CD25~+T淋...

Objective: To observe the effects of moxibustion on CD4~+and CD4~+CD25~+T lymphocytes in peripheral blood of rats with gastric cancer. Methods: A total of 50 healthy SPF SD rats( half male and half female) were randomly divided into 5 groups:the blank group,the sham operation group,the model group,the moxibustion group and the infrared group,with 10 rats in each group. Solid tumor tissue derived from Walker-256 cells was transplanted into the stomach to prepare the tumor model. After modeling,moxibustion group and infrared group were treated 20 mins per day for 21 days. After the intervention,...