期刊论文

Zhang, H.

中文

中国康复医学杂志

1001-1242

2017

32

12

1338-1344

10.3969/j.issn.1001-1242.2017.12.004

国家自然科学基金面上项目

本校为第一且通讯机构

目的:观察电针对骶上脊髓损伤后神经源性膀胱大鼠尿流动力学、髓内细胞凋亡率及脊髓组织中Caspase-3表达的影响。方法:从60只雌性SD大鼠中随机抽取36只,按脊髓横断法制作神经源性膀胱模型后,将符合要求的模型大鼠24只随机分为模型组、电针组各12只,其余24只随机分为空白组、假手术组各12只;术后第19天取“次髎”“中极”“三阴交”“大椎”行电针干预,连续治疗7天后行尿流动力学检测,并用TUNEL法测定髓内细胞凋亡率、Western Blot法测定脊髓组织中Caspase-3蛋白的表达情况。结果:①尿流动力学,与空白组及假手术组比较:模型组、电针组的膀胱基础压力、膀胱最大压力、漏尿点压力升高(P

Objective: To explore the effect of electroacupuncture (EA) on urodynamics, apoptosis rate and Caspase-3 in spinal tissue after completely supersacral spinal cord injury. Method: Among the total of 60 adult female Sprague-Dawley rats, 36 were randomly selected for superspinal cord transection model, 24 compliance model rats were randomly divided into model group and electroacupuncture group with 12 cases in each. Other rats randomly divided into control group, sham operation group with 12 cases in each. electroacupuncture group received electro...