期刊论文

中文

中国现代医学杂志

1005-8982

2006

16

23

3574-3576

10.3969/j.issn.1005-8982.2006.23.016

本校为第一机构

目的 研究还少丹(抗衰老古方)对老龄鼠抗氧化能力的影响.方法 分别将24只老龄小鼠和24只老龄大鼠随机分成药物组与对照组,每组各12只.采用光化学扩增法测定两组小鼠血清中的超氧化物歧化酶(SOD)活性,采用硫代巴比妥酸法测定两组大鼠肝脏中的丙二醛(MDA),用荧光分光光度法测定两组大鼠肝脏中的脂褐素水平,从而观察还少丹对老龄鼠抗氧化能力的影响.结果 还少丹能使老龄小鼠血清SOD活性增强[对照组(21.36±3.10)μkat/g,药物组(31.41±2.51)μ kat/g,t=7.797,P＜0.01],老龄大鼠肝脏中MDA和脂褐素水平明显下降[MDA含量对照组(4.65±0.68)nmol/mgprot,药物组(2.38±0.44)mol/mgprot,t=8.996,p＜0.01]...

[Objective] To observe the anti-oxidation effects of Huanshaodan on aging mice and rats. [Methods] 24 aging mice and 24 aging rats were separately divided into controlled group （n=12） and drug group （n=12）. The activities of superoxide dismutase in mice were detected with photochemical amplification methods. The content of malondialdehyde （MDA） in rats＇ liver tissue was detected with TBA methods. The content of lipofuscin in rats＇ liver tissue was detected with fluorescence spectrometry methods. Then observe the antioxidation effects of...