期刊论文

中文

中国中医基础医学杂志

1006-3250

2013

19

9

1096-1099

国家自然科学基金资助项目(30973717,81273670) 国家自然科学基金青年基金项目(81001518)

本校为第一机构

目的:探讨冠心病血瘀证体质的遗传特征。方法:运用“病例对照”的遗传流行病学家系调查方法,对冠心病血瘀证家系(为观察组)1565人和冠心病非血瘀证家系(为对照组)1553人进行体质调查和分离比、遗传度、遗传模式计算及相关性分析。结果:①冠心病血瘀证先证者及一二级亲属中体质类型均以阳虚质、痰湿质、阴虚质、气虚质所占比例为多;②冠心病血瘀证一二级亲属九种体质类型的遗传度均低于50%。③冠心病血瘀证的发病与主体质存在着相关性(rs =0.879,P

Objective： To explore the Hereditary characteristics of physical constitution of Blood-Stasis Syndrome of Coronary Heart Disease. Methods： 1565 patients of Blood-Stasis Syndrome of Coronary Heart Disease family（observational group） and 1553 patients of non Blood-Stasis Syndrome of Coronary Heart Disease family（eontro group） were included in our study,we taken physical constitution survey and segregation ratio, heredity grade, hereditary, model calculation and relativity analysis by ＂case-controlled＂ hereditary epidemiologieal genealogy ...