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The glial perspective of autism spectrum disorder convergent evidence from postmortem brain and PET studies

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成果类型:
期刊论文
作者:
Liao, Xiaoli;Chen, Miao;Li, Yamin
通讯作者:
Li, YM
作者机构:
[Liao, Xiaoli] Cent South Univ, Xiangya Nursing Sch, Changsha, Hunan, Peoples R China.
[Li, Yamin; Liao, Xiaoli] Cent South Univ, Xiangya Hosp 2, Clin Nursing Teaching & Res Sect, Changsha, Hunan, Peoples R China.
[Chen, Miao] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha, Hunan, Peoples R China.
[Li, Yamin; Li, YM] Cent South Univ, Xiangya Hosp 2, 139 Renmin Middle Rd, Changsha 410011, Hunan, Peoples R China.
通讯机构:
[Li, YM ] C
Cent South Univ, Xiangya Hosp 2, 139 Renmin Middle Rd, Changsha 410011, Hunan, Peoples R China.
语种:
英文
关键词:
Astrocytes;Autism;Microglia;Neuroinflammation
期刊:
Frontiers in Neuroendocrinology
ISSN:
0091-3022
年:
2023
卷:
70
页码:
101064
基金类别:
National Natural Science Founda-tion of China [81873806]; National Natural Science Foun-dation of Hunan Province [514 2019JJ40437]
机构署名:
本校为其他机构
院系归属:
第一中医临床学院
摘要:
OBJECTIVE: The present study aimed to systematically and quantitatively review evidence derived from both postmortem brain and PET studies to explore the pathological role of glia induced neuroinflammation in the pathogenesis of ASD, and discuss the implications of these findings in relation to disease pathogenesis and therapeutic strategies. METHOD: An online databases search was performed to collate postmortem studies and PET studies regarding glia induced neuroinflammation in ASD as compared to controls. Two authors independently conducted the literature search, study selection and data ext...

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