Three new constituents from the Tujia ethnomedicine Swertia punicea Hemsl

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成果类型：

期刊论文

作者：

Yi, Pan;Li, Bin;Zafar, Salman;Ali, Sajjad;Sheng, Wen-Bing;...

通讯作者：

Peng, Cai-Yun;Wang, Wei

作者机构：

[Tang, Yan-Ran; Choudhary, M. Iqbal; Wang, Wei; Ali, Sajjad; Peng, Cai-Yun; Yi, Pan; Peng, CY; Zhou, Fang; Rahman, Atta-ur; Zafar, Salman; Li, Bin; Sheng, Wen-Bing; Mao, Yu] Hunan Univ Chinese Med, Acad Attaur Rahman Belt & Rd Tradit Med Res Ctr, Sch Pharm, ATCM & Ethnomedicine Innovat Dev Int Lab, Changsha, Peoples R China.

[Tang, Yan-Ran; Yi, Pan] Hunan Food & Drug Vocat Coll, Coll Tradit Chinese Med, Changsha, Peoples R China.

[Zafar, Salman] Univ Peshawar, Inst Chem Sci, Peshawar, Pakistan.

[Ali, Sajjad] Karakoram Int Univ, Dept Chem, Gilgit, Pakistan.

[Zhou, Fang; Chen, Wen-Ming] Hunan Univ Chinese Med, Hosp 1, Changsha, Peoples R China.

通讯机构：

[Peng, CY; Wang, W] H

Hunan Univ Chinese Med, Acad Attaur Rahman Belt & Rd Tradit Med Res Ctr, Sch Pharm, ATCM & Ethnomedicine Innovat Dev Int Lab, Changsha, Peoples R China.

语种：

英文

关键词：

(3S,4R,16S,17R)-3,16,23-trihydroxyoleana-11,13(18)-dien-28-aldehyde-3-O-β-D-glucopyranoside;(S)-gentiandiol;1,5R-dihydroxy-3,8S-dimethoxy-5,6,7,8-tetrahydroxanthone;Shuihuanglian;Swertia punicea;antioxidant;gentianaceae

期刊：

Natural Product Research

ISSN：

1478-6419

年：

2023

卷：

期：

页码：

1444-1455

DOI：

10.1080/14786419.2021.2012669

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81673579, 81874369, 82074122]; Natural Science Foundation of Hunan provinceNatural Science Foundation of Hunan Province [2020JJ4064, 2020JJ4463, 2021JJ30502, 2021JJ60062]; Research Foundation of Education Bureau of Hunan Province [20K095, 20A367, 18C1504]; Hunan Provincial first-class pharmaceutical discipline project [2020YX05]; Scientific research project of Hunan University of Chinese Medicine [2019XJJJ003]

机构署名：

本校为第一且通讯机构

院系归属：

第一中医临床学院

药学院

摘要：

Three new constituents: 1,5R-dihydroxy-3,8S-dimethoxy-5,6,7,8-tetrahydroxanthone (1), (3S,4R,16S,17R)-3,16,23-trihydroxyoleana-11,13(18)-dien-28-aldehyde-3-O-beta-D-glucopyranoside (2), and new natural product (S)-gentiandiol (3), along with 41 known compounds were isolated from Tujia ethnomedicine Shuihuanglian, namely, the whole plant of Swertia punicea. Structures of all these compounds were established through extensive spectroscopic techniques, namely 1D, 2D-NMR spectroscopy, HRESIMS analysis, and the absolute configuration of the new compounds was discerned by circular dichroism (CD) spe...

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