期刊论文

中文

中国中医急症

1004-745X

2011

20

8

1246-1247+1262

10.3969/j.issn.1004-745X.2011.08.024

国家自然科学基金青年科学基金项目（30801473） 湖南省自然科学基金项目（00JJY2034 09JJ6041） 湖南省、湖南中医药大学重点学科资助（4101010103）

本校为第一机构

目的 观察内毒素血症兔不同时相的血液白细胞(WBC)计数和凝血功能变化,探讨其与卫气营血阶段性辨证及传变的相关性.方法 将40只新西兰大耳白兔随机分成空白组、1阶段组(注入大肠杆菌内毒素0～2h)、2阶段组(攻毒后2～6h)、3阶段组(攻毒后6～36h);采用静脉注射大肠杆菌内毒素建立内毒索血症模型,检测内毒素血症兔不同时相血液WBC计数及血小板计数(BPC)、凝血功能.结果 1阶段组、2阶段组WBC总数均低于空白组,3阶段组WBC总数比1阶段组、2阶段组升高,与空白组差异无统计学意义.2阶段组、3阶段组BPC较空白组明显下降,以3阶段组为甚.2阶段组、3阶段组凝血酶原时间比空白组延长;3个阶段组的活化凝血酶原...

Objective：To observed these changes of the WBC count and the coagulant function in different phases of endotoxemia rabbit＇s blood and to explored the correlation of these indices with differentiation of Wei-qi-ying-xue syndrome.Methods：40 rabbits were randomly divided into four groups：the normal group,the 1st phase group observed within 2 hours after LPS-infection,the 2nd phase group observed within 2~6 hours after injection and the 3rd group observed within 6~36 hours after injection.The model group was made as endotoxemia rabbit by inject...