期刊论文

中文

中国中医急症

1004-745X

2014

23

5

823-825

10.3969/j.issn.1004-745X.2014.05.016

湖南省教育厅科研项目（118090） 湖南省中医药管理局科研项目（2009030）

本校为第一机构

目的 观察双黄花颗粒的镇咳、祛痰及免疫作用.方法 通过小鼠浓氨水引咳和豚鼠枸橼酸引咳试验,观察双黄花颗粒的镇咳作用;通过小鼠酚红排泄试验观察双黄花的祛痰作用;通过小鼠碳粒廓清试验,观察双黄花颗粒的调节免疫作用.结果 在小鼠氨水引咳试验中,双黄花高、中剂量组浓氨水致咳的潜伏期延长(P＜0.05);双黄花高剂量组小鼠浓氨水致咳的次数显著减少(P＜0.05);在豚鼠枸橼酸引咳试验中,双黄花高剂量组豚鼠枸橼酸引咳的潜伏期和减少咳嗽次数显著延长(P＜ 0.05或P＜0.01);在小鼠酚红排泄试验中,双黄花高剂量组气管酚红排泄量显著增加(P＜0.05);在小鼠碳粒廓清试验中,双黄花高、中剂量组小鼠廓清指数和...

Objective： To evaluate the relieving cough,exspelling phlegm and immunomodulation effects of Shuanghuanghua Granule. Methods： Cough was induced by ammonia in mice and citric acid in guinea pig.The number of cough were recorded to indicate the effect of Shuanghuanghua Granule. The expectorafit activities were by testing the amount of phlegm secreted in mice. Immunomodulation effect was tested by the expectorant carbon clearance in mice. Results： Cough was induced by ammonia in mice,high and middle does groups of Shuanghuanghua Granule could a...