Objective: To systematically evaluate the efficacy and safety of acupuncture combined with medicine on acute ischemic stroke. Methods: According to the Cochrane systematic evaluation method,the included studies were analyzed with Revman 5.3 software. Results: 2 275 cases with acute ischemic stroke were included in 26 studies. The results of meta-analysis showed that the combined acupuncture and drug therapy for acute ischemic stroke could improve the overall efficiency,neurological function defect,daily living ability and safety compared with the control group. Conclusion: Combined acupuncture...