期刊论文

Effects of Pre-electroacupuncture Specific Acupoint on Shaoyang Meridians on 50%PWT and Serum CGRP and SP Content in Migraine Rats

中文

中国中医急症

1004-745X

2019

28

4

572-575

10.3969/j.issn.1004-745X.2019.04.003

中国博士后科学基金面上项目(2017M612566) 湖南省中医药科研计划课题(2017125) 湖南省研究生科研创新项目(CX2017B437).

本校为第一机构

目的观察逆电针少阳经特定穴对偏头痛大鼠的50%缩足阈值(50%PWT)及血清中降钙素基因相关肽(CGRP)、P物质(SP)含量的影响,探讨其可能的作用机制。方法将60只大鼠随机分为空白组(n=20)、模型组(n=20)、逆电针组(n=20),每组又分为造模后30 min组、造模后90 min组,每组各10只。空白组、模型组正常饲养并同电针组同时段捆绑30 min×7 d,逆电针组正常饲养并捆绑行电针治疗30 min×7 d。空白组第8天皮下注射等量0.9%氯化钠注射液,模型组、逆电针组第8天皮下注射硝酸甘油造模,观察治疗前、造模后大鼠行为学、50%PWT,酶联免疫吸附法(ELISA)检测各组血清中CGRP、SP的含量。结果与空白组比较,造模后模型组大...

Objective: To observe the effects of pre-electroacupuncture specific acupoint on Shaoyang meridians on 50%PWT and serum calcitonin gene related peptide(CGRP),Substance P(SP) content in migraine rats,and to explore its possible mechanism. Methods: 60 rats were randomly divided into four groups: the blank group(group C),the model group(group M) and pre-electroacupuncture group(group PEA). Each group was divided into group 30min after modeling and group 90min after modeling,10 rats in each. The rats from group PEA were bound and given electro-acupuncture 30 min per day for 7 days. The other two g...