期刊论文

Effects of Ninghuan Tablet on Endometrial Hismorphology of Rabbits with Cu-IuD

中文

中国中医药科技

1005-7072

2004

11

4

203-204

10.3969/j.issn.1005-7072.2004.04.005

国家中医药管理局科研项目No.0 2 -0 3JL0 7； 湖南省教育厅资助项目No .0 1A0 12；

本校为第一机构

目的:探讨宁环片治疗铜宫内节育器(Cu-IUD)所致子宫异常出血的作用机理.方法:以吲哚美辛作对照,用Olympus光学显微镜观察宁环片对置Cu-IUD家兔子宫内膜表浅微血管变化、血栓形成及螺旋动脉的形态学改变的影响.结果:置Cu-IUD模型组上皮脱落坏死,有大量炎性细胞浸润,宫腔中见多量组织碎片,炎性细胞及渗出液,内膜下小血管部分扩张、充血;间质较疏松水肿,可见较多炎性细胞浸润;高倍视野下子宫内膜表浅微血管总数增多.宁环片各剂量组内膜上皮轻度损伤,内膜炎性细胞较少,偶见小血管扩张、充血,间质较致密,炎性细胞少,其形态变化与对照组吲哚美辛相似.结论:宁环片对上环后子宫异常出血具有良好的治疗作...

Objective:To explore the mechanism of ninghuan tablets for treating endometrorrhagia caused by Cu-IUD.Methods:In constrast with indomethacin,investigating the effects of ninghuan tablets on endometrial superficial microvessel,thrombosis and spiral artery of rabbits with Cu-IUD by olympus light microscope. Results:In model group with Cu-IUD endometrial epithelia were shed,necrosis and infiltrated with a lot of inflammatory cells.Much constitution fragments,inflammatory cells and exudate were observed in uterine cavity.Endometrial small vessels were dilatalted and hyperemia.Interstitial was a li...