Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Luo, Qisheng;Que, Tianshi;Luo, Hongcheng;Meng, Yiliang;Chen, Xiaoping;...

通讯作者：

Fu, Huangde;Huang, Guanglong;Liu, Jia;Tang, Qianli

作者机构：

[Luo, Kunxiang; Yan, Peng; Gong, Juxin; Zheng, Chuanhua; Huang, Haineng; Luo, Qisheng; Fu, Huangde] Youjiang Med Univ Nationalities, Dept Neurosurg, Affiliated Hosp, Baise 533000, Guangxi, Peoples R China.

[Huang, Guanglong; Que, Tianshi] Southern Med Univ, Nanfang Hosp, Dept Neurosurg, Guangzhou 510515, Guangdong, Peoples R China.

[Hu, Rentong; Luo, Hongcheng] Youjiang Med Univ Nationalities, Dept Lab Med, Affiliated Hosp, Baise 533000, Guangxi, Peoples R China.

[Meng, Yiliang] Baise Peoples Hosp, Dept Oncol, Baise 533000, Guangxi, Peoples R China.

[Chen, Xiaoping] Guangxi Zhuang Autonomous Reg Peoples Hosp, Dept Neurol, Nanning 530021, Guangxi, Peoples R China.

通讯机构：

[Fu, Huangde; Liu, Jia; Tang, Qianli] Y

[Huang, Guanglong] S

[Tang, Qianli] H

Youjiang Med Univ Nationalities, Dept Neurosurg, Affiliated Hosp, Baise 533000, Guangxi, Peoples R China.

Southern Med Univ, Nanfang Hosp, Dept Neurosurg, Guangzhou 510515, Guangdong, Peoples R China.

语种：

英文

关键词：

DEAD box helicase 5;DEAD box helicase 17;Glioma;Radiotherapy;Prognosis

期刊：

PATHOLOGY RESEARCH AND PRACTICE

ISSN：

0344-0338

年：

2020

卷：

216

期：

页码：

152828-

DOI：

10.1016/j.prp.2020.152828

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81760450, 81702473]; Guangxi Natural Science Foundation of China [2017GXNSFAA198322]; President Fund of Nanfang Hospital [2016C019]

机构署名：

本校为通讯机构

院系归属：

中西医结合学院

摘要：

Recent researches indicated Ddx5 and Ddx17 play crucial roles in tumorigenesis. However, the study of Ddx5 and Ddx17 in glioma remains a little. Our study investigated their expression in glioma and evaluated its association with clinical factors and prognostic significance. The expression of Ddx5 and Ddx17 were both upregulated in glioma tissues compared to normal brain tissues, and a significant positive correlation between Ddx5 and Ddx17 expression was identified by statistical analysis. Immunohistochemical staining verified the expression o...

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Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas

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