期刊论文

Xu, Yin;Zhu, Y

英文

Frontiers in Immunology

1664-3224

2023

14

1203707

10.3389/fimmu.2023.1203707

This study was supported by grants from the National Natural Science Foundation of China (81874466, 81904176), Natural Science Foundation of Hunan Province (2021JJ30531, 2023JJ60044), Scientific Research Foundation of Hunan Provincial Department of Education (21B0389), Hunan Province Administration of Traditional Chinese Medicine (B2023079), Clinical Medical Technology Innovation Guide Project of Hunan Province (2021SK51413), and domestic first-class construction discipline of Chinese Medicine in Hunan University of Chinese Medicine.

本校为第一且通讯机构

BackgroundPrevious observational or retrospective studies have suggested an association between inflammatory bowel disease (IBD) and herpes virus infections. Using Mendelian randomization (MR) approach, our objective was to determine whether there was a causal association between IBD and herpes virus infections. MethodsIn genome-wide association study (GWAS) datasets of the International Inflammatory Bowel Disease Genetics Consortium, we obtained genetic instrumental variables for three phenotypes from 34,652 participants (12,882 IBD cases and 21,770 controls), 27,432 participants [6,968 ulcer...