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Aptamer-based biosensors for virus protein detection

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成果类型:
期刊论文
作者:
Lou, Beibei;Liu, Yanfei;Shi, Meilin;Chen, Jun;Li, Ke;...
通讯作者:
Liu, Z.
作者机构:
[Liu, Zhenbao; Wang, Ting; Li, Ke; Chen, Jun; Wu, Yuwei; Lou, Beibei] Cent South Univ, Xiangya Sch Pharmaceut Sci, Dept Pharmaceut, Changsha 410013, Hunan, Peoples R China.
[Liu, Yanfei; Tan, Yifu; Chen, Liwei; Liu, Xiaoqin; Jiang, Ting] Cent South Univ, Coll Chem & Chem Engn, Dept Pharmaceut Engn, Changsha 410083, Hunan, Peoples R China.
[Shi, Meilin] Xuzhou Med Univ, Sch Med Imaging, Xuzhou 221004, Jiangsu, Peoples R China.
[Peng, Dongming] Hunan Univ Chinese Med, Sch Pharm, Dept Med Chem, Changsha 410208, Peoples R China.
[Liu, Zhenbao] Cent South Univ, Mol Imaging Res Ctr, Changsha 410008, Hunan, Peoples R China.
通讯机构:
[Liu, Z.] D
Department of Pharmaceutics, Xiangya School of Pharmaceutical Sciences, Central South University, Hunan Province, Changsha, China
语种:
英文
关键词:
Aptamer;Detection;Virus;Aptasensor
期刊:
TrAC - Trends in Analytical Chemistry
ISSN:
0165-9936
年:
2022
卷:
157
页码:
116738
基金类别:
This work was financially supported by the Hunan Provincial Natural Science Foundation for Distinguished Young Scholars ( 2022JJ10086 ), Innovation-Driven Project of Central South University ( 2020CX048 ), the National Natural Science Foundation of China ( 81301258 ), the Natural Science Foundation of Hunan Province ( 2019JJ60071 , 2020JJ4680 ), the Natural Science Foundation of Changsha ( kq2202131 ), the Shenghua Yuying Project of Central South University , the Postgraduate Innovation Project of Central South University ( 2020zzts819 , 2020zzts408 , 2020zzts409 , 2021zzts0977 , 2021zzts0979 ), and the Open-End Fund for the Valuable and Precision Instruments of Central South University .
机构署名:
本校为其他机构
院系归属:
药学院
摘要:
Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for clinical control and treatment of virus infection. Aptamers are small single-stranded oligonucleotides (DNAs or RNAs). In this review, we summarized aptasensors for virus detection in recent years according to the classification of the viral target protein, and illustrated common detection mechanisms in the aptasensors (colorimetry, fluorescence assay, surface plasmon resonance (SPR), surface-enhanced raman spectroscopy (SERS), electrochemical detectio...

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