期刊论文

Effects of Exercise Rehabilitation and Shenfu Injection on Hemodynamics in Rats with Cardiomyopathy Heart Failure

中文

湖南中医药大学学报

1674-070X

2017

37

7

715-718

10.3969/j.issn.1674-070X.2017.07.005

国家自然科学基金项目（81373550）； 湖南省大学生研究性学习和创新性实验计划项目（2016-298）； 湖南中医药大学青年教师科研基金（2015-32）；

本校为第一机构

目的 观察运动康复联合参附注射液对心肌病所致心力衰竭大鼠血流动力学的影响.方法 将50只SD雄性大鼠随机分为安静对照组(10只)与造模组(40只),造模组大鼠采用盐酸多柔比星腹腔注射7周造模,造模成功后的36只大鼠,按随机数字表法,分为模型组、参附组、运动康复组、运动康复参附组,每组9只.分别用生理盐水、参附注射液、运动康复、运动康复联合参附注射液干预4周,检测大鼠左室收缩压峰值(LVSP)、左舒张末压力(LVEDP)、左室等容收缩末期压力上升最大速度(+dp/dtmax)、左室压力下降最大速度(-dp/dtmax)等血流动力学指标.结果 与模型组比较,参附组、运动康复组、运动康复参附组在LVSP、LVEDP、+dp/dt...

Objective To observe the effect of exercise rehabilitation combined with Shenfu injection on hemodynamics in rats with heart failure induced by cardiomyopathy. Methods 50 SD rats were randomly divided into the control group and model group, model group rats was injected doxorubicin hydrochloride intraperitoneally for 7 weeks, After success-ful modeling, the rats were divided into model group, Shenfu group, exercise group, exercise and Shenfu group according to the random number table method, 6 in each group. They will be treated with sali ne, Shenfu injection, exercise rehabilitation, exercise...