Protective effect of Lizhong Pill on nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rats: Possible involvement of TNF and IL-17 signaling pathways.

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成果类型：

期刊论文

作者：

Yu, Chang*;Qiu, Jingyue*;Xiong, Meng*;Ren, Baoping*;Zhong, Meiqi*;...

通讯作者：

Yu, Chang;Qiu, Jingyue;Xiong, Meng;Ren, Baoping;Zhong, Meiqi;Zhou, Sainan;Li, Yuejun;Zeng, Meiyan;Song, Houpan

作者机构：

[Qiu, Jingyue; Xiong, Meng; Zhong, Meiqi; Yu, Chang; Ren, Baoping; Song, Houpan] Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan Province, China

[Yu, Chang] College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address: yuc@stu.hnucm.edu.cn

[Qiu, Jingyue] College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address: QiuJY@stu.hnucm.edu.cn

[Xiong, Meng] College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address: xiongmeng@stu.hnucm.edu.cn

[Ren, Baoping] College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address: rbp@stu.hnucm.edu.cn

通讯机构：

[Yu, Chang; Qiu, Jingyue; Zhong, Meiqi; Xiong, Meng; Song, Houpan; Zeng, Meiyan; Ren, Baoping] C

[Zhou, Sainan; Li, Yuejun] D

College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address:

Department of Gastroenterology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan Province, China. Electronic address:

Department of Oncology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, Hunan Province, China. Electronic address:

语种：

英文

关键词：

Gastric mucosal injury;IL-17;Indomethacin;Lizhong Pill;TNF

期刊：

Journal of Ethnopharmacology

ISSN：

0378-8741

年：

2024

卷：

318

期：

Pt B

页码：

116991

DOI：

10.1016/j.jep.2023.116991

机构署名：

本校为第一且通讯机构

院系归属：

中医学院

摘要：

ETHNOPHARMACOLOGICAL RELEVANCE: The traditional Chinese medicine formula Lizhong Pill (LZP) and its herbal constituents are frequently utilized in Asian (China, Saudi Arabia, India, Japan, etc.) and some European (Russia, Sweden, UK, etc.) nations to treat various gastrointestinal ailments. AIM OF THE STUDY: This study aimed to investigate the protective impact and potential mechanism of LZP against indomethacin (IND)-induced gastric mucosal injury in rats. MATERIAL AND METHODS: Using a biochemical kit, we investigated the levels of superoxide dismutase (SOD), catalase (CAT), and glutathione S...

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Protective effect of Lizhong Pill on nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rats: Possible involvement of TNF and IL-17 signaling pathways.

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