Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tasneem, Shumaila;Liu, Bin;Li, Bin;Choudhary, M. Iqbal;Wang, Wei*

通讯作者：

Wang, Wei

作者机构：

[Tasneem, Shumaila; Liu, Bin; Choudhary, M. Iqbal; Li, Bin; Wang, Wei] Hunan Univ Chinese Med, Sch Pharm, TCM & Ethnomed Innovat & Dev Int Lab, Changsha 410208, Hunan, Peoples R China.

[Liu, Bin] Hunan Univ, State Key Lab, Hunan Prov Key Lab Plant Funct Genom & Dev Regula, Coll Biol, Changsha 410082, Hunan, Peoples R China.

[Tasneem, Shumaila; Choudhary, M. Iqbal] Univ Karachi, Int Ctr Chem & Biol Sci, Dr Panjwani Ctr Mol Med & Drug Res, Karachi 75270, Pakistan.

[Tasneem, Shumaila] Dow Univ Hlth Sci Gulzar E Hijri, Fac Pharmaceut Sci, Dept Pharmacol, Dow Coll Pharm, Ojha Campus,Suparco Rd,KDA Scheme 33, Karachi, Pakistan.

[Wang, Wei] Hunan Univ Chinese Med, Sch Pharm, 300 Xueshi Rd,Hanpu Sci & Technol Pk, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Wang, Wei] H

[Wang, Wei] P

Hunan Univ Chinese Med, Sch Pharm, 300 Xueshi Rd,Hanpu Sci & Technol Pk, Changsha 410208, Hunan, Peoples R China.

Pharm Sch Off, TCM & Ethnomed Innovat & Dev Int Lab, 300 Xueshi Rd,Hanpu Sci & Technol Pk, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

*Caffeoylquinic acid (PubChem CID: 10155076);*Cistanoside (PubChem CID: 73157724);*Clinical trials;*Curcuma longa;*Curcumin (PubChem CID: 969516);*Cytokines;*Epigallocatechin-3-gallate (PubChem CID: 10050483);*Forsythoside A (PubChem CID: 5281773);*Ligustilide (PubChem CID: 5319022);*Molecular inflammation;*NF-kappaB pathway;*Tectoridin (PubChem CID: 5281810);*Triptolide (PubChem CID: 118701083);*Ursolic acid (PubChem CID: 64945);*Yakuchinone A (PubChem CID: 133145)

期刊：

Pharmacological Research

ISSN：

1043-6618

年：

2019

卷：

139

期：

页码：

126-140

DOI：

10.1016/j.phrs.2018.11.001

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81673579, 81703819, 81874369]; Hunan Provincal Department of Science and Technology [2018SK2113]; State Administration of TCM [ZYBZH-Y-HUN-23]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2016JJ6118, 2018JJ3386]; Administration of Traditional Chinese Medicine of Hunan Province [201673]

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

Except for an essential step for the pathology of multiple diseases including atherosclerosis and rheumatoid arthritis, inflammation is an imperative therapeutic target for developing novel approaches for pharmacological interventions. Thus, molecular understanding of inflammation not only revealed the mechanisms of drug action and their biological targets but also has spawned innovative maneuvers to influence multifaceted biological systems, providing new prospects for drug designing and suggesting important new implications for existing clinical medicine. Meanwhile, modulation of inflammatio...

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Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents

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