The role and mechanism of TXNDC5 in cardio-oncology: Killing two birds with one stone?

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

An, Na;Zhang, Xiaoyu;Lin, Hongyuan;Xu, Qianqian;Dai, Qianqian;...

通讯作者：

Shang, HC;Xing, YW

作者机构：

[An, Na; Li, Xiao] Beijing Univ Chinese Med, DongZhimen Hosp, Beijing, Peoples R China.

[Dai, Qianqian; Shang, Hongcai; Han, Songjie; Kong, Yifan; Shang, HC; An, Na; Li, Xiao] Beijing Univ Chinese Med, Key Lab Chinese Internal Med, Minist Educ, Beijing, Peoples R China.

[Shang, Hongcai; Shang, HC] Beijing Univ Chinese Med, Dongfang Hosp, Beijing, Peoples R China.

[Xing, Yanwei; Xing, YW] China Acad Chinese Med Sci, Guanganmen Hosp, Beijing, Peoples R China.

[Zhang, Xiaoyu] China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing, Peoples R China.

通讯机构：

[Shang, HC ] B

[Xing, YW ] C

Beijing Univ Chinese Med, Key Lab Chinese Internal Med, Minist Educ, Beijing, Peoples R China.

Beijing Univ Chinese Med, Dongfang Hosp, Beijing, Peoples R China.

China Acad Chinese Med Sci, Guanganmen Hosp, Beijing, Peoples R China.

语种：

英文

关键词：

Cancer;Cardio-oncology;Cardiotoxicity;Cardiovascular disease;Thioredoxin domain containing 5

期刊：

Current Problems in Cardiology

ISSN：

0146-2806

年：

2025

卷：

期：

页码：

102951

DOI：

10.1016/j.cpcardiol.2024.102951

基金类别：

support and author disclosures This work was supported by Noncommunicable Chronic Diseases-National Science and Technology Major Project (NO. 2023ZD0502700&2023ZD0502705), the Chinese Medicine inheritance and innovation “thousand million” Talents Project (Qihuang Project) Qihuang Scholars (NO. RS086),the Postdoctoral Fellowship Program of China Postdoctoral Science Foundation (grant number GZC20230322) and the China Postdoctoral Science Foundation (certificate number 2024M760285). All other authors have reported that they

机构署名：

本校为通讯机构

院系归属：

中西医结合学院

摘要：

Cardio-oncology has emerged as a new translational and clinical field owing to the growing repertory of cancer therapy. To date, there is a lack of effective pharmacological therapy to target cardiotoxicity. Cardio-oncology, which began by investigating the negative effects of cancer medicines on cardiovascular system, has since grown to include research into the similarities between cardiovascular disease (CVD) and cancer. Thioredoxin domain-containing protein 5 (TXNDC5) belongs to the protein disulfide isomerase (PDI) family. Many diseases, including CVD and cancer, improperly express TXNDC5...

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The role and mechanism of TXNDC5 in cardio-oncology: Killing two birds with one stone?

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