Objective:To optimize ethanol extraction technology of Rutongruanjian tablets. Methods:Ethanol extraction technolo- gy were optimized by orthogonal tests with yield of extract and Tetrahydropalmatine transferring ratio as indexes, and with The con cen-tration and amount of ethanol, extraction time as factors. Results:The best alcohol extraction process was as follows:70 % etha- nol of 6 fold volume,soaking 0.5h , ex-tracting 2 times with 1. Oh for each time. Conclusion: The optimum extraction process was reasonabl...