期刊论文

Liu, W.-L.

中文

中草药

0253-2670

2014

45

18

2619-2624

10.7501/j.issn.0253-2670.2014.18.009

国家自然科学基金资助项目（30901971,81270055） 湖南省自然科学基金项目（14JJ2110,14JJ7061）

本校为第一且通讯机构

目的以补阳还五汤为模型药方,探索有效成分群(部位)溶度参数的变化规律。方法用均匀设计、星点设计安排实验方案,用改良反相气相色谱法(IGC)测定溶度参数值,用 SPSS 软件拟合曲线方程。结果得出有效成分黄芪甲苷(X_1)、阿魏酸(X_2)、芍药苷(X_3)、川芎嗪(X_4)的溶度参数的递推方程为Y=–69.016+435.277 X_1X_2+336.966 X_2X_4+487.702 X_3X_4-54.575 X_1 ~2-59.696 X_2X_3(r=1.000,P

Objective: To take Buyanghuanwu Decoction as a model for exploring the variable rule of solubility parameters for the effective components group (fraction). Methods: To arrange the experiment design by uniform design and central composite plan, to determine the solubility parameter values with the modified inverse gas chromatography (IGC), and to fit the curve equation using SPSS software. Results: The recursive equation for the major active component including astragaloside (X1), ferulic acid (X2), paeoniflorin (X3), and ligustrazine (X4) was ...