期刊论文

Chemical constituents from leaves of Styrax japonicus

Li, J.

中文

中草药

0253-2670

2019

50

1

30-35

10.7501/j.issn.0253-2670.2019.01.007

国家中医药管理局“药用植物学”重点学科(国中医药发[2009]30号) 湖南省大学生研究性学习和创新性实验计划项目(湘教通[2018]255号) 郴州五盖山天时生态农业科技开发有限公司委托课题(50010103) 湖南省高校科技创新团队资助项目(湘教通[2010]212号) 湖南中医药大学中药学一流学科资助项目(校行科字[2018]3号).

本校为第一且通讯机构

目的 对野茉莉Styrax japonicus的叶进行化学成分研究.方法 通过硅胶、Sephadex LH-20凝胶柱色谱及重结晶等方法 进行分离和纯化,根据理化性质、波谱数据进行结构鉴定.结果 从野茉莉叶70％乙醇提取物三氯甲烷萃取部位分离得到16个化合物,包括9个苯丙素和7个其他类化合物,分别鉴定为nectandrin B(1)、豆甾醇(2)、荚果蕨素(3)、eupomatenoid-7 (4)、β-谷甾醇(5)、去氢二异丁香酚(6)、4-oxo-4[(3β,22E)-stigmasta-5,22-dien-3-yloxy]butanoic acid (7)、4-(3-methory-4-hydroxy) pheny-3-methyl-3-buten-2-one (8)、熊果酸(9)、香草酸(10)、(+)-(7S,8R,8'R)-4,8’-dihydroxy-3-methoxy-1’,2’,3...

Objective To study the chemical constituents from the leaves of Styrax japonicus. Methods Seventeen compounds including nine phenylpropanoids and seven other constituents were isolated from the chloroform fraction of the 70% ethanol extract of leaves of S. japonicus, using column chromatography over silica gel and Sephadex LH-20 as well as the method of recrystallization. Results On the basis of physical and chemical properties combined with spectral data analysis, their structures were elucidated as nectandrin B (1), stigmasterol (2), matteuci...