3,4-Seco-lupane type triterpenoids are pentacyclic triterpenoids, which are abundant in the plants of Acanthopanax genus. Pharmacological studies have shown that 3,4-seco-lupane type triterpenoids have a wide range of biological activities, such as anti-inflammatory, antibacterial, and anti-tumor activities. 3,4-seco-Lupane type triterpenoids have potential development and application value. By referring to relevant domestic and foreign literature reports, the research progress of 3,4-seco-lupane type triterpenoids is reviewed in terms of chemi...