As a natural source compound, norlignan compounds have complex and diverse structure types with a wide of sources. Norlignan can be divided into norlignan and norneolignan by the difference of connection mode and position of two phenylpropanoid molecules. Norlignan have various biological activities such as anti-tumor, anti-allergy, anti-inflammatory, antioxidant, anti-HIV, and hormone-like effects. This review mainly describes the structure types and biological activities of natural sources of norlignan, providing a basis for the research deve...