期刊论文

Effect of Wuhu Decoction on autophagy in dendritic cells and levels of inflammatory factors IL-17A and IL-17F in RSV-induced asthmatic mice

Wang, M.-Q.

中文

中草药

0253-2670

2021

52

3

718-726

10.7501/j.issn.0253-2670.2021.03.014

国家自然科学基金资助项目（81774368）； 湖南省自然科学基金资助项目（2018JJ6114）； 湖南省研究生科研创新资助项目（CX20190580）； 湖南中医药大学中医学国内一流学科建设学科项目（4901-020002002）；

本校为第一且通讯机构

Objective: To observe the effect of Wuhu Decoction (五虎汤) on dendritic cells autophagy, inflammatory factor interleukin-17A (IL-17A), and interleukin-17F (IL-17F) in RSV-induced asthmatic mice. Methods: Asthmatic mice model was established by RSV and ovalbumin (OVA). Mice were randomly divided into control group, model group, Wuhu Decoction low-, medium-, high-dose (1.6, 3.2, 6.4 g/kg) groups, dexamethasone (1.82 mg/kg) group and rapamycin (1 mg/kg) group. After given with drugs for 14 d, HE staining was used to observe the pathology of lung,...