期刊论文

Scientific connotation of “summer withering with good quality” based on dynamic monitoring of chemical constituents at different growth and development stages of Prunella vulgaris

Xia, B.-H.

中文

中草药

0253-2670

2021

52

07

2082-2090

10.7501/j.issn.0253-2670.2021.07.025

长沙市科技计划项目（kq2004063）； 湖南中医药大学中药学开放基金项目（2020ZYX11）；

本校为第一机构

目的基于紫外（UV）和高效液相（HPLC）全息指纹图谱,化学模式识别技术与多成分定量相结合的方法,整合评价不同生长发育时期的49批夏枯草Prunella vulgaris样品化学成分的变化规律,从而阐明夏枯草由草到药的演变过程,解释夏枯草"夏枯质优"的科学内涵。方法建立不同生长发育时期49批夏枯草样品的UV和HPLC全息指纹图谱,采用主成分分析（principal component analysis,PCA）、偏最小二乘法-判别分析（partial leastsquares-discriminant analysis,PLS-DA）对其进行评价,筛选出影响夏枯草分类的特异性吸收波段,并对主要差异性化学成分进行含量测定。结果建立了不同生长发育时期49批夏枯草样品的UV和...

Objective: Based on the UV and HPLC fingerprints of Prunella vulgaris samples, combined with multi-component quantitative analysis and chemical pattern recognition methods, the changes of chemical components in 49 batches of P. vulgaris samples at different growth stages were evaluated, so as to clarify the evolution process of P. vulgaris from herbs to medicines, and explain the scientific connotation of "summer withering with good quality" of P. vulgaris. Methods: UV and HPLC holographic fingerprints of 49 batches of P. vulgaris samples at di...