Simultaneous determination of synephrine, arecoline, and norisoboldine in Chinese patent medicine Si-Mo-Tang oral liquid preparation by strong cation exchange high performance liquid chromatography

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成果类型：

期刊论文

作者：

Yi, Yue-Neng;Cheng, Xue-Mei;Liu, Ling-An;Hu, Gao-Yun;Wang, Zheng-Tao;...

通讯作者：

Cai, Guang-Xian

作者机构：

[Huang, Ke-Long; Yi, Yue-Neng] Cent S Univ, Coll Chem & Chem Engn, Changsha, Hunan, Peoples R China.

[Cai, Guang-Xian] Hunan Univ Tradit Chinese Med, Changsha 410007, Hunan, Peoples R China.

[Wang, Chang-Hong; Cheng, Xue-Mei; Wang, Zheng-Tao] Shanghai Univ Tradit Chinese Med, Minist Educ, Key Lab Standardizat Chinese Med, Shanghai, Peoples R China.

[Deng, Yi-De; Yi, Yue-Neng] Hunan Engn & Technol Res Ctr Gastroenterol Drugs, Changsha, Hunan, Peoples R China.

[Deng, Yi-De; Yi, Yue-Neng; Liu, Ling-An] Hunan Hansen Pharmaceut Co, Yiyang, Peoples R China.

通讯机构：

[Cai, Guang-Xian] H

Hunan Univ Tradit Chinese Med, 113 Shaoshan Middle Rd, Changsha 410007, Hunan, Peoples R China.

语种：

英文

关键词：

Alkaloids;Areca catechu;Aucklandia luppa;Chinese patent medicine;Citrus aurantium;Lindera aggregata

期刊：

Pharmaceutical Biology

ISSN：

1388-0209

年：

2012

卷：

期：

页码：

832-838

DOI：

10.3109/13880209.2011.637505

基金类别：

National Basic Research Program of ChinaNational Basic Research Program of China [2009CB523002]; National Action of Technology Personnel Servicing Enterprise Program of China [2009FJ5049, 2009GJD20014]; Foundation of Hunan Science and Technology Committee [2009XK6032, 2009-152]; Foundation of Hunan Educational Committee [09CY001]

机构署名：

本校为通讯机构

摘要：

CONTEXT: Chinese patent medicine Si-Mo-Tang oral liquid preparation (SMT) is composed of Aucklandia luppa Decne (Compositae), Citrus aurantium Linn (Rutaceae), Lindera aggregata (Sims) Kosterm (Lauraceae), and Areca catechu Linn (Arecaceae). Studies of SMT have been impeded due to the lack of quality control methods. OBJECTIVE: This study aimed to simultaneously determine three alkaloids including synephrine, arecoline, and norisoboldine in SMT for the first time. MATERIALS AND METHODS: A strong cation exchange (SCX) high performance liquid chromatography (HPLC) method was developed to simulta...

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Simultaneous determination of synephrine, arecoline, and norisoboldine in Chinese patent medicine Si-Mo-Tang oral liquid preparation by strong cation exchange high performance liquid chromatography

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