Objective: To investigate the Optimal Alcohol Extraction Process of Traditional Chinese Medicine Uncaria. Methods: The single factor index study was established by the total content of Rhynchophylline and Isorhynchophylline to find out the optimum solvent concentration and extraction times by alcohol extract. Reasonable and feasible soak time, extraction time and the amount of alcohol as the factors were determined, through Orthogonal experimental design. Results: The concentration of ethanol 70%, two times extraction, soak time 0.5 h before...