期刊论文

中文

中医药导报

1672-951X

2016

22

13

97-100,103

10.13862/j.cnki.cn43-1446/r.2016.13.035

本校为其他机构

目的：建立湿疹软膏中薄荷脑与冰片的含量测定方法。方法：采用气相色谱法,用乙酸乙酯提取薄荷脑、冰片,以水杨酸甲酯为内标物,使用PEG-20M色谱柱,用氢火焰离子检测器检测。结果：通过方法学考察,薄荷脑在0.05012~0.5012 mg/m L范围内呈良好的线性关系,平均回收率为99.60%（n=9）。冰片在0.06032~0.6032 mg/m L范围内呈良好的线性关系,平均加样回收率为99.24%（n=9）。结论：该方法简便、准确、重复性好、精密度高。可用于湿疹软膏的工艺研究。

Objective： To establish a method to determine menthol and borneo1 in eczema ointment. Meth- ods： Menthol and borneol contents were determined by GC, extraction of menthol and borneol with ethyl acetate, Methylmethyl salicylate used as the internal standard, using the PEG-20M column, FID as detector. Results： A good linearity between the concentration and peak area value when the concentrations of menthol at 0.05012 - 0.50121 mg/mL. The average recovery of menthol is 99.60% （n=9）.A good linearity between the concentration and peak area valu...