期刊论文

中文

中医药导报

1672-951X

2017

23

14

23-26+30

10.13862/j.cnki.cn43-1446/r.2017.14.007

81603482:国家自然科学基金 2016JJ6115:湖南省自然科学基金 2015JJ6057:湖南省自然科学基金

本校为第一机构

Objective： To observe the effect of Zhitong Jiangu Decoction （止痛健骨方, ZTJGD） on cartilage TNF-α expression in knee osteoarthritis, and its correlation with articular cartilage Mankin＇s score. Methods： The 90 rabbits were randomly divided into normal control group, model control group, positive drug group, ZTJGD low dose group, ZTJGD high dose group, each group with 18 rats in each, the preparation of rabbit model of KOA papain intra-articular injection of and model verification is successful, ZTJGD low dose group, high dose group, to ...