This paper expounds the origin and compatibility of Zhizhu Pills, and summarizes the different clinical applications field extended by LI Dong-yuan and later medical doctors according to the chief sign and concun'ent pattern. It summarizes the flexible application of Zhizhu Pills in the treatment of functional dyspepsia, gastroesophageal reflux disease and funetional constipation. The Zhizhu pill is well-prepared, and it has the function of fortifying the spleen and dispersing food, moving Qi and transforming dampness. It mainly t...