Objective: To observe the effect of Banxia Xiexin decoction (半夏泻心汤, BXXXD) on intestinal flora and intestinal mucosa in mice with spleen-deficiency constipation. Methods: The 24 Kumning mice were randomly and equally divided into normal group, model group, Zhizhu decoction (枳术汤) group, and BXXXD group. The mice in model group, Zhizhu decoction group, and BXXXD group were given decoction of senna by garage; 7 days later, these mice were given an irregular diet for 8 days to establish a mouse model of spleendeficiency constipation. ...