Objeetive: To observe the changes of serum 5-HT levels before and after treatment in patients with post-stroke depression (PSD) to explore the possible mechanism of Xingshen Qibi acupuncture (醒神启闭针刺法) on treating this disease. Methods: The 60 PSD patients were randomly divided into treatment group and control group, 30 cases in each. The treatment group was treated with Xingshen Qibi acupuncture, and the control group was treated with oral duloxetine, both were treated for 28 days. Serum 5-HT concentrations, HAMD scores, and modifi...