Objective: By establishing the acute myocardial ischemia (AMI) model, to investigate the effects of Xintongtai granule on new blood vessels density, the expression of Notch1, D114 protein in rats with AMI. Methods: The rats were randomly divided into six groups, except for the 10 rats in sham -operation group, the other rats were ligatured left anterior of coronary artery to establish the rat models of AML Then randomly di-vided into the model group, high-, medium- and low-dose of Xintongtai groups, and Shexiang Baoxin pill (麝香保心丸)group, w...