Objective: To study the protective effect of Citrus total flavonoids on ovarian injury induced by chemotherapeutic drugs in rats. Methods: Fifty female SD rats were randomly divided into five groups. The ovar-ian injury model was made by intraperitoneal injection of cyclophosphamide in four groups and the control group was made by intraperitoneal injection of cyclophosphamide in one group. SD rats were randomly divided into low-dose citrus flavonoids group, high-dose citrus flavonoids group, Kuntai capsule (坤泰胶囊)group and model control grou...